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Availability: In stock

DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt

M-1865

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-1865.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 309.00
CHF 287.37 (7%)
M-1865.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'236.00
CHF 1'149.48 (7%)
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Details

The fluorogenic HIV-1 protease substrate DABCYL-Gaba-SQNYPIVQ-EDANS consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.
Item Number 4030716
APC Number 72-3-30
One Letter Code DABCYL-Gaba-SQNYPIVQ-EDANS
Molecular Formula C₇₃H₉₇N₁₇O₁₈S
Relative Molecular Mass 1532.74
CAS Registry Number [127134-13-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords HIV protease FRET substrate
Areas of Interest Infectious Disease

M-1865

Enzyme Substrates Inhibitors
Retropepsin    
HIV-2 Protease