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Availability: In stock

H-Phe-Arg-βNA · 2 HCl

K-1450

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
K-1450.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 165.00
CHF 153.45 (7%)
K-1450.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 494.00
CHF 459.42 (7%)
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Details

Substrate for dipeptidyl aminopeptidase I (cathepsin C).
A broad-spectrum efflux pump inhibitor in gram-negative bacteria. PAbN has been evaluated as an adjunct to antibiotics, as efflux in bacteria mediates antibiotic resistance. Vecchione et al. demonstrated that Phe-Arg-β-naphthylamide could potentiate drug activity also against a gram-positive bacterium. PAbN permeabilizes the outer membrane of gram-negative bacteria (Lamers et al.).
Item Number 4000885
Synonyms MC-207110, PAbN
Molecular Formula C₂₅H₃₀N₆O₂ · 2 HCl
Relative Molecular Mass 519.47
CAS Registry Number [100929-99-5]
Source Synthetic
Storage Conditions -20 ± 5 °C

K-1450

Enzyme Substrates Inhibitors
Dipeptidyl-Peptidase I (DPP I)