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Availability: In stock

Ac-Trp-Glu-His-Asp-AMC

I-1715

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
I-1715.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
I-1715.0025 25 mg Ships within 3-5 business days  
CHF 824.00
CHF 766.32 (7%)
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Details

With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently than I-1630. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
Item Number 4027662
APC Number 81-7-18
One Letter Code Ac-WEHD-AMC
Synonyms Ac-WEHD-AMC
Molecular Formula C₃₈H₄₀N₈O₁₁
Relative Molecular Mass 784.78
CAS Registry Number [189275-74-9]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE substrate
Areas of Interest Apoptosis & Necrosis

I-1715

Enzyme Substrates Inhibitors
Caspase-1 (ICE)