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Availability: In stock

Ac-Asp-Glu-Val-Asp-AMC ammonium salt

I-1660

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
I-1660.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 227.00
CHF 211.11 (7%)
I-1660.0025 25 mg Ships within 3-5 business days  
CHF 906.00
CHF 842.58 (7%)
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Details

A continuous fluorometric assay employing Ac-DEVD-AMC has been developed for the measurement of caspase-3, a cysteine protease also called apopain, Yama or CPP-32. The design of this substrate Ac-DEVD-AMC was based on the substrate motif that has been used successfully with caspase-1, using the poly(ADP-ribose) polymerase cleavage site P₁-P₄ tetrapeptide.
Item Number 4026262
APC Number 81-6-30
One Letter Code Ac-DEVD-AMC
Synonyms Ac-DEVD-AMC, Apopain Substrate
Molecular Formula C₃₀H₃₇N₅O₁₃
Relative Molecular Mass 675.65
CAS Registry Number [169332-61-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-3 substrate
Areas of Interest Apoptosis & Necrosis

Bachem product citations

L.M.Faddah et al., African Journal of Pharmacy and Pharmacology, 7, 2639 (2013)

I-1660

Enzyme Substrates Inhibitors
Caspase-3 (CPP-32; Yama; Apopain)    
Caspase-7 (ICE-LAP3; Mch3; CMH-1)