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Availability: In stock

Boc-Arg-Val-Arg-Arg-AMC acetate salt

I-1645

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
I-1645.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 258.00
CHF 239.94 (7%)
I-1645.0100 100 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 773.00
CHF 718.89 (7%)
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Details

The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4·10³ M⁻¹s⁻¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4.
Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.
Item Number 4018735
APC Number 81-7-40
One Letter Code Boc-RVRR-AMC
Molecular Formula C₃₈H₆₂N₁₄O₈
Relative Molecular Mass 843.01
CAS Registry Number [136132-77-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin substrate

I-1645

Enzyme Substrates Inhibitors
Furin    
Proprotein Convertase 4