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Availability: In stock

Suc-Leu-Leu-Val-Tyr-AMC

I-1395

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
I-1395.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
I-1395.0100 100 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 618.00
CHF 574.74 (7%)
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Details

The fluorogenic substrate Suc-LLVY-AMC is used for measuring the chymotrypsin-like activity of the 20S proteasome, in combination with e.g. Bz-VGR-AMC, I-1085 (for assaying its trypsin-like activity) and Z-LLE-AMC, I-1945 (for determining its PGPH activity).
Suc-LLVY-AMC is also cleaved by a chymotrypsin-like enzyme from sperm extract of the ascidian Halocynthia roretzi, a strong inhibitor of fertilization. The substrate has also been used to analyze the chymotrypsin-like activity of trypsins as well as chymase from rat mast cells. Furthermore, Suc-LLVY-AMC is a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.
Item Number 4011369
APC Number 81-1-07
One Letter Code Suc-LLVY-AMC
Synonyms Chymotrypsin Substrate III, Fluorogenic
Molecular Formula C₄₀H₅₃N₅O₁₀
Relative Molecular Mass 763.89
CAS Registry Number [94367-21-2]
Source Synthetic
Storage Conditions -20 ± 5 °C

Bachem product citations

I-1395

Enzyme Substrates Inhibitors
Chymase    
Papain    
Multicatalytic Endopeptidase Complex    
Calpain    
Carboxypeptidase C    
Calpain-2    
Envelysin    
Proteasome Endopeptidase Complex    
Kexin