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Availability: In stock

Iberiotoxin
Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH
(Disulfide bonds between Cys⁷ and Cys²⁸/Cys¹³ and Cys³³/Cys¹⁷ and Cys³⁵)

H-9940

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-9940.0100 0.1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 232.00
CHF 215.76 (7%)
H-9940.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 927.00
CHF 862.11 (7%)
H-9940.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'545.00
CHF 1'436.85 (7%)
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Details

Iberiotoxin (IbTx), from the venom of the scorpion Buthus tamulus, shows 68% sequence homology with charybdotoxin, another scorpion-derived peptidyl toxin. Although these two toxins both inhibit the high conductance Ca²⁺ activated K⁺ channel, they appear to bind at different sites on the channel and modulate channel activity by different mechanisms. Thus, iberiotoxin can be used to selectively study the function of the high conductance Ca²⁺ activated K⁺ channel.
Item Number 4030755
APC Number 41-0-20
One Letter Code pEFTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
Molecular Formula C₁₇₉H₂₇₄N₅₀O₅₅S₇
Relative Molecular Mass 4230.91
CAS Registry Number [129203-60-7]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Ion Channel Modulating Agents