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Details
The investigation of the adjuvant activity of this muramyl peptide on humoral and cellular immune responses showed that it augments the mitogenic responses of splenic lymphocytes to phytohemagglutinin and lipopolysaccharide and the formation of antibodies to sheep erythrocytes in mice. In addition, it potentiated polyclonal B cell activation in vivo and in vitro.
Item Number
4015937
Synonyms
Romurtide, Muroctasin, MDP-Lys(L 18), Ac-muramyl-Ala-D-Isogln-Lys(stearoyl)-OH
Molecular Formula
C₄₃H₇₈N₆O₁₃
Relative Molecular Mass
887.13
CAS Registry Number
[78113-36-7]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Adjuvant
Areas of Interest
Immunomodulating Agents
Links / Documents:
Brochures:
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Product citations
G.Baschang,
Tetrahedron,
45,
6331 (1989)
C.P.Robinson,
Drugs Future,
14,
432 (1989)