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Tyr-PDGF A-Chain (194-211)
H-Tyr-Gly-Arg-Pro-Arg-Glu-Ser-Gly-Lys-Lys-Arg-Lys-Arg-Lys-Arg-Leu-Lys-Pro-Thr-OH

H-8335

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-8335.0500 0.5 mg Ships within 1 business day  
CHF 289.00
CHF 268.77 (7%)
H-8335.1000 1 mg Ships within 1 business day  
CHF 515.00
CHF 478.95 (7%)
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Details

Alternative splicing of the platelet-derived growth factor A-chain RNA gives rise to two distinct A-chain forms that differ in the presence or absence of a hydrophilic carboxy-terminus by 18 amino acids (residues 194-211). H-8335, which corresponds to this region and is N-terminally tyrosinated for convenient radioiodination, was shown to bind specifically to several normal and transformed cell lines. Furthermore, this peptide and its non-tyrosinated homolog (H-2736) inhibit the stimulation of DNA synthesis and cell division by normal human serum as well as attenuate the growth-promoting activity of several serum growth factors.
Item Number 4031139
One Letter Code YGRPRESGKKRKRKRLKPT
Molecular Formula C₁₀₁H₁₈₁N₃₉O₂₅
Relative Molecular Mass 2341.80
CAS Registry Number [137132-69-5]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Growth Factors