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Cdc25A (80-93) (human) trifluoroacetate salt
H-Thr-Asp-Ser-Gly-Phe-Cys-Leu-Asp-Ser-Pro-Gly-Pro-Leu-Asp-OH trifluoroacetate salt

H-8314

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-8314.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 179.00
CHF 166.47 (7%)
H-8314.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 306.00
CHF 284.58 (7%)
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Details

The abundance of Cdc25A fluctuates periodically during the cell division cycle, which is primarily modulated by the ubiquitin-proteasome system, through the action of two ubiquitin ligase complexes, Anaphase Promoting Complex/Cyclosome and Skp1/Cul1/F-box protein. Ubiquitylation and degradation occurs at mitotic exit and in G1 due to the presence of a destruction motif (KEN-box) in Cdc25A, while phosphorylation events regulate Cdc25A protein stability in S phase both in unperturbed cells and in cells exposed to DNA damaging agents or DNA replication inhibitors.
Item Number 4104898
One Letter Code TDSGFCLDSPGPLD
Molecular Formula C₆₀H₉₀N₁₄O₂₄S
Relative Molecular Mass 1423.52
CAS Registry Number [851538-67-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Cancer Research