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Teplow's Amyloid β-Protein (1-42) (scrambled II) trifluoroacetate salt
H-Tyr-His-Ala-Gly-Val-Asp-Lys-Glu-Val-Val-Phe-Asp-Glu-Gly-Ala-Gly-Ala-Glu-His-Gly-Leu-Ala-Gln-Lys-Ile-Val-Arg-Gly-Phe-Gly-Val-Ser-Asp-Val-Ser-Met-Ile-His-Ile-Asn-Leu-Phe-OH trifluoroacetate salt

H-8282

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-8282.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 330.00
CHF 306.90 (7%)
H-8282.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 495.00
CHF 460.35 (7%)
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Details

This peptide is a specifically designed negative control in studies with Abeta42. It is "scrambled", which means it contains the same amino acids as Abeta42, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-42) does not show a number of phenomena regularly observed with Abeta42 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.
Item Number 4104168
One Letter Code YHAGVDKEVVFDEGAGAEHGLAQKIVRGFGVSDVSMIHINLF
Synonyms β-Amyloid (1-42) (scrambled II), Aβ42 scrambled II
Molecular Formula C₂₀₃H₃₁₁N₅₅O₆₀S
Relative Molecular Mass 4514.10
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease