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Defensin 5 (human) trifluoroacetate salt
H-Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg-OH trifluoroacetate salt
(Disulfide bonds, air oxidized)

H-8252

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-8252.0100 0.1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 290.00
CHF 269.70 (7%)
H-8252.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 950.00
CHF 883.50 (7%)
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Details

Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine.
Reduction or absence of HD 5 release in the intestinal mucosa has been associated with susceptibility to enteric pathogens, changes in composition of the microbiota, and disruption of intestinal immune homeostasis.
As a biomarker, HD 5 might be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn's colitis (high levels of HD 5).
Item Number 4102158
One Letter Code ATCYCRTGRCATRESLSGVCEISGRLYRLCCR
Synonyms Defensin HD 5, HD 5, Human α-defensin 5, α-Defensin 5 (human)
Molecular Formula C₁₄₄H₂₃₈N₅₀O₄₅S₆
Relative Molecular Mass 3582.18
Source Synthetic
Storage Conditions -20 ± 5 °C