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FSL-1-FLAG trifluoroacetate salt
H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH trifluoroacetate salt

H-7926

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-7926.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 290.00
CHF 269.70 (7%)
H-7926.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 490.00
CHF 455.70 (7%)
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Details

The lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of a M. salivarium lipoprotein, is capable of inducing the cell surface expression of ICAM-1 in human gingival fibroblasts. It furthermore revealed an activity to induce production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. FSL-1 also activated macrophages to produce tumor necrosis factor alpha. Overall, results by Okusawa and coworkers suggest that the diacylglyceryl and the peptide portions of FSL-1 are indispensable for the expression of biological activities and for the recognition by Toll-like receptors 2 and 6. Furthermore, the same authors conclude that the recognition of FSL-1 by Toll-like receptors 2 and 6 apparently is hydrophobic.
Item Number 4099727
One Letter Code Pam₂CGDPKHPKSFDYKDDDDK
Synonyms Fibroblast Stimulating Lipopeptide 1 FLAG-tag
Molecular Formula C₁₂₅H₁₉₈N₂₄O₃₇S
Relative Molecular Mass 2661.15
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Immunomodulating Agents