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SPLUNC1 (22-39) trifluoroacetate salt
H-Gly-Gly-Leu-Pro-Val-Pro-Leu-Asp-Gln-Thr-Leu-Pro-Leu-Asn-Val-Asn-Pro-Ala-OH trifluoroacetate salt

H-7352

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-7352.0500 0.5 mg Ships within 3-5 business days  
CHF 125.00
CHF 116.25 (7%)
H-7352.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
H-7352.5000 5 mg Ships within 3-5 business days  
CHF 840.00
CHF 781.20 (7%)
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Details

SPLUNC1 is an endogenous inhibitor of the epithelial sodium channel (ENaC) which is responsible for Na⁺ and fluid absorption across colon, kidney, and airway epithelia. The partial sequence GGLPVPLDQTLPLNVNPA (SPLUNC1 22-39) corresponds to the ENaC inhibitory domain of SPLUNC1. As ENaC hyperactivity contributes to the development of cystic fibrosis in the lungs, the fragment could help to develop new strategies for the treatment of this genetic disorder.
Item Number 4081062
One Letter Code GGLPVPLDQTLPLNVNPA
Molecular Formula C₈₂H₁₃₅N₂₁O₂₅
Relative Molecular Mass 1815.10
CAS Registry Number [1421132-47-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Ion Channel Modulating Agents