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Dermcidin-1L (human) trifluoroacetate salt
H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH trifluoroacetate salt

H-7316

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-7316.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 125.00
CHF 116.25 (7%)
H-7316.1000 1 mg Ships within 3-5 business days  
CHF 225.00
CHF 209.25 (7%)
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Details

The protein dermcidin expressed in the sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1).
Dermcidin and naturally occurring fragments as DCD-1L do not perturb membrane permeability and bind to distinct surface molecules. Niyonsaba et al. have reported that DCD-1L stimulates keratinocytes to generate cytokines and chemokines such as TNF-α, IL-8, CXCL10, and CCL20.
Item Number 4061590
One Letter Code SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
Synonyms DCD-1L (human)
Molecular Formula C₂₁₀H₃₅₉N₅₇O₇₁
Relative Molecular Mass 4818.50
CAS Registry Number [478898-18-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Antimicrobial peptide from human sweat