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Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH acetate salt
(Disulfide bonds between Cys¹ and Cys¹⁵/Cys³ and Cys¹¹)

H-6995

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-6995.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 412.00
CHF 383.16 (7%)
H-6995.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'648.00
CHF 1'532.64 (7%)
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Details

Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil.
ET-1 plays a central role in lung fibrosis.
Item Number 4040254
One Letter Code CSCSSLMDKECVYFCHLDIIW
Synonyms ET-1 (human, bovine, dog, mouse, porcine, rat)
Molecular Formula C₁₀₉H₁₅₉N₂₅O₃₂S₅
Relative Molecular Mass 2491.94
CAS Registry Number [117399-94-7] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Vasoconstrictor

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