Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

Colivelin trifluoroacetate salt
H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt

H-6336

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-6336.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 205.00
CHF 190.65 (7%)
H-6336.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 351.00
CHF 326.43 (7%)
Add to Wish List
Add to Compare

Details

Colivelin is a hybrid peptide which mediates neuroprotection against Alzheimer's disease (AD)-relevant insults. It is composed of activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA(C8R)HNG17, a potent humanin derivative. Colivelin completely suppressed death induced by overexpressing familial AD-causative genes and amyloid β-protein (1-43) (H-1586) at a concentration of 100 fM. Intraperitoneally administered peptide suppressed memory impairment caused by the muscarinic acetylcholine receptor antagonist, 3-quinuclidinyl benzylate, indicating that a substantial portion of intraperitoneally administered colivelin passes through the blood brain barrier.
Item Number 4050404
APC Number 13-1-22
One Letter Code SALLRSIPAPAGASRLLLLTGEIDLP
Molecular Formula C₁₁₉H₂₀₆N₃₂O₃₅
Relative Molecular Mass 2645.14
CAS Registry Number [867021-83-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Neuroprotective peptide
Areas of Interest Alzheimer's Disease