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Apelin-17 (human, bovine, mouse, rat) trifluoroacetate salt
H-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH trifluoroacetate salt

H-6302

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-6302.0001 1 mg Ships within 3-5 business days  
CHF 227.00
CHF 211.11 (7%)
H-6302.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 906.00
CHF 842.58 (7%)
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Details

Apelin-17 is an endogenous ligand of the human orphan G protein-coupled receptor APJ, reported to act as a coreceptor of CD4 for human and simian immunodeficiency viruses. Apelin-17 and apelin-13 represent the predominant molecular forms of apelin present in the whole brain, hypothalamus, and plasma. Like apelin-13, apelin-17 exhibited a high activity on extracellular acidification rate and strongly inhibited forskolin-stimulated cAMP production in CHO cells expressing the human or the rat apelin receptor. The peptide might play a crucial role in the maintenance of body fluid homeostasis by counteracting AVP (arginine vasopressin) actions through inhibition of AVP neuron activity and AVP release.
Item Number 4050029
One Letter Code KFRRQRPRLSHKGPMPF
Synonyms Preproapelin (61-77) (human, bovine, mouse, rat), Apelin Precursor (61-77) (human, bovine, mouse, rat)
Molecular Formula C₉₆H₁₅₆N₃₄O₂₀S
Relative Molecular Mass 2138.58
CAS Registry Number [217082-57-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Regulator of body fluid homeostasis
Areas of Interest Virology