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Tyr-(D-Dab⁴,Arg⁵,D-Trp⁸)-cyclo-Somatostatin-14 (4-11) trifluoroacetate salt
H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) trifluoroacetate salt

H-6276

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-6276.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 309.00
CHF 287.37 (7%)
H-6276.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'236.00
CHF 1'149.48 (7%)
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Details

High affinity ligand for all five somatostatin receptors (sst1-sst5). In AtT-20 mouse anterior pituitary tumor cells which mainly express sst2 and sst5 receptors the binding affinity of this somatostatin analog was found to be higher than that of somatostatin-14 (H-1490) and octreotide (H-5972). In a model of epileptogenesis, however, KE 108 did not exhibit antiepileptic activity suggesting that the high potency and efficacy of a synthetic ligand to all known somatostatin receptors may not reproduce entirely the effects of the natural ligand.
Item Number 4041674
Synonyms KE 108
Molecular Formula C₆₇H₈₅N₁₅O₁₁
Relative Molecular Mass 1276.51
CAS Registry Number [496849-46-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Cancer Research