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TIMP-2 (145-168) (human, bovine) trifluoroacetate salt
H-Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile-OH trifluoroacetate salt
(Disulfide bond)

H-5998

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-5998.0500 0.5 mg Ships within 3-5 business days  
CHF 129.00
CHF 119.97 (7%)
H-5998.1000 1 mg Ships within 3-5 business days  
CHF 206.00
CHF 191.58 (7%)
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Details

TIMP-2 (145-168) (human, bovine) corresponding to loop 6 of tissue inhibitor of metalloproteinase-2 (TIMP-2) is a potent inhibitor of angiogenesis. It displayed a metalloproteinase (MMP)-independent anti-angiogenic activity which could be separated from the MMP-dependent activity of TIMP-2. In contrast to the MMP-dependent activity which only inhibited embryonic neovascularization it was able to inhibit both embryonic and mitogen-stimulated angiogenesis in vivo.
Item Number 4043445
One Letter Code ECLWMDWVTEKNINGHQAKFFACI
Synonyms Metalloproteinase Inhibitor 2 (145-168) (human, bovine), CSC-21K (145-168) (human, bovine), Tissue Inhibitor Of Metalloproteinases-2 (145-168) (human, bovine)
Molecular Formula C₁₃₁H₁₈₉N₃₃O₃₅S₃
Relative Molecular Mass 2882.34
CAS Registry Number [1872435-10-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Angiogenesis