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Neuromedin U-25 (human) trifluoroacetate salt
H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH₂ trifluoroacetate salt

H-5538

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-5538.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
H-5538.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 361.00
CHF 335.73 (7%)
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Details

Neuromedin U is a neuropeptide which is widely distributed in the gut and central nervous system. Initially isolated from porcine spinal cord it was named for its uterine contractile activity. In fasted rats neuromedin U expression in certain brain areas is lower than in fed rats. In animal studies with neuromedin-23 (rat) overnight food intake is significantly reduced indicating that neuromedin U may be a physiological regulator of food intake. IC₅₀ values for the binding of neuromedin U-25 (human) to the human neuromedin U receptors NMU1R and NMU2R are 2.7 nM and 1.8 nM, respectively.
Item Number 4037521
APC Number 62-0-54
One Letter Code FRVDEEFQSPFASQSRGYFLFRPRN-NH₂
Synonyms NMU-25 (human)
Molecular Formula C₁₄₁H₂₀₃N₄₁O₃₈
Relative Molecular Mass 3080.42
CAS Registry Number [312306-89-1] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Obesity Research