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Availability: In stock

Cortistatin-17 (human) trifluoroacetate salt
H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH trifluoroacetate salt
(Disulfide bond)

H-5536

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-5536.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 258.00
CHF 239.94 (7%)
H-5536.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 412.00
CHF 383.16 (7%)
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Details

Cortistatin-17 shows structural similarities to somatostatin. The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin. Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14. Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat. It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms.
Item Number 4037520
APC Number 34-7-35
One Letter Code DRMPCRNFFWKTFSSCK
Molecular Formula C₉₆H₁₃₉N₂₇O₂₄S₃
Relative Molecular Mass 2151.53
CAS Registry Number [189450-19-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Somatostatin-related neuropeptide