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(Met¹⁸⁶)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt
H-Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val-OH trifluoroacetate salt

H-4938

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4938.0001 1 mg Ships within 3-5 business days  
CHF 103.00
CHF 95.79 (7%)
H-4938.0005 5 mg Ships within 3-5 business days  
CHF 412.00
CHF 383.16 (7%)
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Details

This modified sequence of the gp100 epitope gp(209-217) (H-4106), in which a methionine replaced the natural threonine at position 2, bound to the HLA-A2 molecule with greater affinity than the unmodified peptide and was shown to have an increased ability to generate melanoma-reactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide hold promise for the development of novel cancer immunotherapies.
Item Number 4034137
APC Number 55-0-13
One Letter Code IMDQVPFSV
Synonyms (Met¹⁸⁶)-Melanocyte Lineage-Specific Antigen GP100 (185-193) (human, bovine, mouse), (Met¹⁸⁶)-Melanoma-Associated ME20 Antigen (185-193) (human, bovine, mouse), (Met¹⁸⁶)-ME20M/ME20S (185-193) (human, bovine, mouse), (Met¹⁸⁶)-ME20-M/ME20-S (185-193) (human, bovine, mouse), (Met¹⁸⁶)-95 kDa Melanocyte-Specific Secreted Glycoprotein (185-193) (human, bovine, mouse), Disomotide
Molecular Formula C₄₇H₇₄N₁₀O₁₄S
Relative Molecular Mass 1035.23
CAS Registry Number [181477-43-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C