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Details
Potent oxytocin antagonist with a pA₂ value of 7.35 ± 0.08. (d(CH₂)₅¹,Tyr(Me)²,Orn⁸)-Vasotocin has been used to support the hypothesis that pituitary secretion of oxytocin is associated with coactivation of centrally projecting brain oxytocin pathways, some of which are causally related to the induced inhibition of food intake. Furthermore, this compound competitively inhibited arginine vasotocin (AVT) contractions without affecting AVT efficacy.
Item Number
4034493
APC Number
66-0-16
Synonyms
[Pmp1, Tyr(OMe)2, Orn8] Vasotocin
Molecular Formula
C₄₈H₇₄N₁₂O₁₂S₂
Relative Molecular Mass
1075.32
CAS Registry Number
[77327-45-8] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Pituitary & Hypothalamic Hormones
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