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α-CGRP (8-37) (mouse, rat) trifluoroacetate salt
H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH₂ trifluoroacetate salt

H-4924

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4924.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 315.00
CHF 292.95 (7%)
H-4924.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,261.00
CHF 1,172.73 (7%)
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Details

α-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37) (H-2746). Furthermore, it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.
Item Number 4034544
APC Number 22-5-18
One Letter Code VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH₂
Synonyms Calcitonin Gene-Related Peptide I (8-37) (mouse, rat), CGRP-I (8-37) (mouse, rat)
Molecular Formula C₁₃₈H₂₂₄N₄₂O₄₁
Relative Molecular Mass 3127.56
CAS Registry Number [129121-73-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords CGRP antagonist