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Proadrenomedullin (1-20) (human)
H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH₂

H-4916

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4916.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
H-4916.1000 1 mg Ships within 3-5 business days  
CHF 330.00
CHF 306.90 (7%)
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Details

Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.
Item Number 4034490
APC Number 22-1-19
One Letter Code ARLDVASEFRKKWNKWALSR-NH₂
Synonyms PAMP, Pro-Adrenomedullin N-20, human
Molecular Formula C₁₁₂H₁₇₈N₃₆O₂₇
Relative Molecular Mass 2460.87
CAS Registry Number [150238-87-2]
Source Synthetic
Storage Conditions -20 ± 5 °C