Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

NFAT Inhibitor trifluoroacetate salt
H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH trifluoroacetate salt

H-4874

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4874.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
H-4874.1000 1 mg Ships within 3-5 business days  
CHF 361.00
CHF 335.73 (7%)
Add to Wish List
Add to Compare

Details

The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.
Item Number 4034010
One Letter Code MAGPHPVIVITGPHEE
Molecular Formula C₇₅H₁₁₈N₂₀O₂₂S
Relative Molecular Mass 1683.95
CAS Registry Number [249537-73-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C