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NFAT Inhibitor trifluoroacetate salt
H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4874.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
H-4874.1000 1 mg Ships within 3-5 business days  
CHF 368.00
CHF 342.24 (7%)
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The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.
Item Number 4034010
Molecular Formula C₇₅H₁₁₈N₂₀O₂₂S
Relative Molecular Mass 1683.95
CAS Registry Number [249537-73-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C