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Interferon-Inducible T Cell α-Chemoattractant (human)
H-Phe-Pro-Met-Phe-Lys-Arg-Gly-Arg-Cys-Leu-Cys-Ile-Gly-Pro-Gly-Val-Lys-Ala-Val-Lys-Val-Ala-Asp-Ile-Glu-Lys-Ala-Ser-Ile-Met-Tyr-Pro-Ser-Asn-Asn-Cys-Asp-Lys-Ile-Glu-Val-Ile-Ile-Thr-Leu-Lys-Glu-Asn-Lys-Gly-Gln-Arg-Cys-Leu-Asn-Pro-Lys-Ser-Lys-Gln-Ala-Arg-Leu-Ile-Ile-Lys-Lys-Val-Glu-Arg-Lys-Asn-Phe-OH
(Disulfide bonds between Cys⁹ and Cys³⁶/Cys¹¹ and Cys⁵³)

H-4606

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4606.0010 10 µg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 391.00
CHF 363.63 (7%)
H-4606.0050 50 µg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'566.00
CHF 1'456.38 (7%)
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Details

Synthetically produced; cysteines are oxidized. Contains BSA (low levels of endotoxins) in a ratio of 1:50. The chemokine I-TAC (interferon-inducible T cell α-chemoattractant), a non-ELR C-X-C chemokine, is regulated by interferon and has potent chemoattractant activity for interleukin-2-activated T cells, but not for freshly isolated unstimulated T cells, neutrophils, or monocytes. It has been suggested that I-TAC constitutes a major chemoattractant for effector T cells, involved in the pathophysiology of neuroinflammatory disorders, although it may play a role in the migration of activated T cells during interferon-dominated immune response.
Item Number 4030497
One Letter Code FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
Synonyms I-TAC (human), CXCL11 (human)
Molecular Formula C₃₆₈H₆₁₉N₁₀₇O₉₈S₆
Relative Molecular Mass 8303.02
CAS Registry Number [1927911-33-8]
Source Synthetic
Storage Conditions -20 ± 5 °C