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Orexin A (human, mouse, rat) trifluoroacetate salt
Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH₂ trifluoroacetate salt
(Disulfide bonds between Cys⁶ and Cys¹²/Cys⁷ and Cys¹⁴)

H-4172

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-4172.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 270.00
CHF 251.10 (7%)
H-4172.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 385.00
CHF 358.05 (7%)
H-4172.5000 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'540.00
CHF 1'432.20 (7%)
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Details

Orexin A (OXA, hypocretin-1) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin A to rats stimulated food consumption in a dose-dependent manner. The effect persisted at 4 h after injection, as orexin A seems to be resistant to peptidases. Orexin A specifically binds a G protein-coupled receptor, OX₁R (IC₅₀ = 20 nM to displace 50 % of radiolabeled orexin A bound to this receptor). Orexin A produced in the amygdala induces wakefulness and plays a role in the induction of human emotions. Narcolepsy has been associated with orexin deficiency.
H-4172 also corresponds to bovine, canine, ovine, and porcine orexin A.
Item Number 4028262
APC Number 46-2-70
One Letter Code pEPLPDCCRQKTCSCRLYELLHGAGNHAAGILTL-NH₂
Synonyms Hypocretin-1 (human, mouse, rat), Orexin A, human, bovine, rat, mouse
Molecular Formula C₁₅₂H₂₄₃N₄₇O₄₄S₄
Relative Molecular Mass 3561.16
CAS Registry Number [205640-90-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C

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