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Availability: In stock

(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P
H-D-Arg-Pro-Lys-Pro-D-Trp-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH₂

H-3992

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-3992.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 185.00
CHF 172.05 (7%)
H-3992.0005 5 mg Ships within 1 business day  
CHF 742.00
CHF 690.06 (7%)
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Details

This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
Item Number 4031292
APC Number 70-9-19
One Letter Code rPKPwQwFwLL-NH₂
Synonyms [DArg1, DTrp5,7,9, Leu11] Substance P
Molecular Formula C₈₁H₁₁₀N₂₀O₁₂
Relative Molecular Mass 1555.89
CAS Registry Number [122481-75-8]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Cancer Research