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Availability: In stock

(Arg¹⁵,Asp¹⁶·²⁵,Pro¹⁸·²¹·²³,Val²²,Ile²⁴)-Amyloid β-Protein (15-25)
H-Arg-Asp-Leu-Pro-Phe-Phe-Pro-Val-Pro-Ile-Asp-OH

H-3904

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-3904.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 113.00
CHF 105.09 (7%)
H-3904.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 453.00
CHF 421.29 (7%)
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Details

The undecapeptide RDLPFFPVPID (iAβ11) has a similar degree of hydrophobicity as the native amyloid β-peptide (Aβ), but with a low propensity to adopt a β-sheet conformation. It is therefore called anti-β-sheet peptide or β-sheet inhibitor. iAβ11 binds to Aβ, inhibits Aβ fibril formation and partially disaggregates preformed fibrils in vitro. This anti-β-sheet peptide may serve as a starting point to design inhibitors of amyloidogenesis in vivo.
Item Number 4027529
One Letter Code RDLPFFPVPID
Synonyms iAβ11
Molecular Formula C₆₄H₉₄N₁₄O₁₆
Relative Molecular Mass 1315.54
CAS Registry Number [182912-63-6]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease