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Availability: In stock

H-Phe-Glu-Trp-Thr-Pro-Gly-Tyr-Trp-Gln-Pro-Tyr-Ala-Leu-Pro-Leu-OH

H-3738

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-3738.0001 1 mg Ships within 3-5 business days  
CHF 278.00
CHF 258.54 (7%)
H-3738.0005 5 mg Ships within 3-5 business days  
CHF 1'112.00
CHF 1'034.16 (7%)
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Details

AF11377, FEWTPGYWQPYALPL, blocked IL-1α-binding to the type I IL-1 receptor with IC₅₀ = 1.9 nM. AF11377 blocked IL-1-driven responses in human and monkey cells. This is the first example of a high affinity peptide that binds to a cytokine receptor and acts as a cytokine antagonist.
Item Number 4027198
One Letter Code FEWTPGYWQPYALPL
Synonyms AF11377
Molecular Formula C₉₅H₁₂₂N₁₈O₂₂
Relative Molecular Mass 1868.12
CAS Registry Number [171492-13-0]
Source Synthetic
Storage Conditions -20 ± 5 °C