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Availability: In stock

Ac-Tyr(PO₃H₂)-Glu-Glu-Ile-Glu-OH

H-3724

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-3724.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
H-3724.0005 5 mg Ships within 3-5 business days  
CHF 824.00
CHF 766.32 (7%)
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Details

Ac-pYEEIE showed high affinity for the pp60src SH2 domain with an IC₅₀ = 0.5 µM. Additionally it blocked binding of various SH2 domain constructs to platelet-derived growth factor kinase, i.e. Src with IC₅₀ = 1.35 µM, Abl with IC₅₀ = 15.3 and Grb2 at 100 µM by 44.25%. It did not bind to Syp (N-terminal) and PLC (C-terminal) SH2 constructs.
Item Number 4027154
Molecular Formula C₃₂H₄₆N₅O₁₇P
Relative Molecular Mass 803.71
CAS Registry Number [159439-02-8]
Source Synthetic
Storage Conditions -20 ± 5 °C

Product citations

A.Shahripour et al., Bioorg. Med. Chem. Lett., 6, 1209 (1996)