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IFN-γ Antagonist
H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH

H-2722

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2722.0500 0.5 mg Ships within 1 business day  
CHF 378.00
CHF 351.54 (7%)
H-2722.1000 1 mg Ships within 1 business day  
CHF 683.00
CHF 635.19 (7%)
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Details

This peptide derived from the ligand binding site of the human γ-interferon (IFN-γ) receptor is an antagonist of human IFN-γ. It inhibited human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an approximate IC₅₀ of 35 µM. Immobilized peptide specifically bound recombinant human IFN-γ (H-1728). Tyrosine substitution at residue 121 allowed facile quantification and conjugation of the peptide.
Item Number 4030819
Synonyms (Tyr¹²¹,Cys(Acm)¹²²)-IFN-γ Receptor (120-141) (human)
Molecular Formula C₁₁₅H₁₉₄N₃₄O₃₄S
Relative Molecular Mass 2629.08
CAS Registry Number [158040-83-6]
Source Synthetic
Storage Conditions -20 ± 5 °C