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α-Synuclein (61-95) (human) trifluoroacetate salt
H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH trifluoroacetate salt

H-2598

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2598.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 195.00
CHF 181.35 (7%)
H-2598.1000 1 mg Ships within 3-5 business days  
CHF 351.00
CHF 326.43 (7%)
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Details

The 35 amino acid peptide NAC (α-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or α-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.
Item Number 4026207
APC Number 62-5-25
One Letter Code EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFV
Synonyms NAC, α-Synuclein (61-95) (human), Non-β-Amyloid Component of Alzheimer's Disease (NAC), Non-Aβ Component of Alzheimer's Disease Amyloid
Molecular Formula C₁₄₁H₂₃₅N₃₉O₄₉
Relative Molecular Mass 3260.65
CAS Registry Number [154040-19-4] net
Source Synthetic
Storage Conditions -20 ± 5 °C