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Availability: In stock

Fibronectin Fragment (1377-1388)
H-His-Ser-Arg-Asn-Ser-Ile-Thr-Leu-Thr-Asn-Leu-Thr-OH

H-2572

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2572.0001 1 mg Ships within 3-5 business days  
CHF 216.00
CHF 200.88 (7%)
H-2572.0005 5 mg Ships within 3-5 business days  
CHF 865.00
CHF 804.45 (7%)
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Details

Fibronectin fragment H-2572 inhibited fibronectin binding to the platelet membrane glycoprotein (GP) IIb/IIIa by interacting directly with this receptor, with an IC₅₀ of about 104 µM. HSRNSITLTNLT also inhibited the binding of fibrinogen to GPIIb/IIIa, as well as platelet aggregation. This indicates that this peptide derived from the cell binding domain of fibronectin comprises an RGD-independent GPIIb/IIIa binding site localized within the residues His¹³⁷⁷ and Ile¹³⁸².
Item Number 4026199
One Letter Code HSRNSITLTNLT
Molecular Formula C₅₆H₉₇N₁₉O₂₀
Relative Molecular Mass 1356.50
CAS Registry Number [162257-99-0]
Source Synthetic
Storage Conditions -20 ± 5 °C