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Acetyl-Amyloid β/A4 Protein Precursor₇₇₀ (96-110) (cyclized)
Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH₂
(Disulfide bond)

H-2232

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2232.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 103.00
CHF 95.79 (7%)
H-2232.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 413.00
CHF 384.09 (7%)
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Details

This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of ¹²⁵I-labeled APP to heparin (IC₅₀= 10⁻⁷M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Item Number 4025760
APC Number 62-1-15
One Letter Code Ac-NWCKRGRKQCKTHPH-NH₂
Synonyms Ac-APP₇₇₀ (96-110) (cyclized), β-Amyloid / A4 Protein Precursor (APP) (96-110), analog
Molecular Formula C₈₁H₁₂₈N₃₂O₁₉S₂
Relative Molecular Mass 1918.24
CAS Registry Number [289634-54-4]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease