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(Phe¹³,Tyr¹⁹)-MCH (human, mouse, rat) trifluoroacetate salt
H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr-OH trifluoroacetate salt
(Disulfide bond)

H-2218

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2218.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 155.00
CHF 144.15 (7%)
H-2218.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 258.00
CHF 239.94 (7%)
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Details

This derivative suitable for iodination is a further development of natural MCH, which loses its activity upon iodination. The labeled compound enabled to establish the first radioreceptor assay for MCH. Saturation binding experiments with this peptide, radioiodinated, revealed a Bmax of 1090 and a Kd of 1 · 10⁻¹⁰M for receptors in G4F-7 mouse melanoma cells.
Item Number 4026028
One Letter Code DFDMLRCMLGRVFRPCWQY
Synonyms (Phe¹³,Tyr¹⁹)-Melanin-Concentrating Hormone (MCH) (human, mouse, rat)
Molecular Formula C₁₀₉H₁₆₀N₃₀O₂₆S₄
Relative Molecular Mass 2434.92
CAS Registry Number [160201-86-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C

Product citations

R.Drozdz et al., Peptides 1994, Proceedings of the 23rd European Peptide Symposium, Braga, p. 785, H.L.S.Maia, ed., Escom, Leiden, (1995)