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Cyclo(-Gly-Tyr(PO₃H₂)-Val-Pro-Met-Leu)

H-2062

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-2062.0001 1 mg Ships within 3-5 business days  
CHF 464.00
CHF 431.52 (7%)
H-2062.0005 5 mg Ships within 3-5 business days  
CHF 1'854.00
CHF 1'724.22 (7%)
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Details

The cyclic hexapeptide c(GYVPML), corresponding to the autophosphorylation segment around Tyr⁷⁵¹ of the PDGF receptor B subunit, serves as an inhibitor of receptor tyrosine kinase/src homology region 2 (SH2) interactions that mediate mitogenic signal transduction pathways.
Item Number 4025469
Molecular Formula C₃₂H₄₉N₆O₁₀PS
Relative Molecular Mass 740.82
CAS Registry Number [158778-21-3]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Protein-Tyrosine Kinases

Product citations

M.Nomizu et al., Tetrahedron, 50, 2691 (1994)

H-2062

Enzyme Substrates Inhibitors
Protein Tyrosine Kinase