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Availability: In stock

Antipain
[(S)-1-Carboxy-2-phenyl-ethyl]-carbamoyl-Arg-Val-Arg-aldehyde

H-1765

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-1765.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 309.00
CHF 287.37 (7%)
H-1765.0250 250 mg Ships within 3-5 business days  
CHF 1'236.00
CHF 1'149.48 (7%)
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Details

A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin (N-1000). H-1765 inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.
Item Number 4030290
Molecular Formula C₂₇H₄₄N₁₀O₆
Relative Molecular Mass 604.71
CAS Registry Number [37691-11-5]
EINECS Number 253-631-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Inhibitor of Cys- and Ser-proteases
Areas of Interest Cancer Research

H-1765

Enzyme Substrates Inhibitors
Clostripain    
Peptidyl-Lys Metalloendopeptidase    
Tissue Kallikrein    
Plasmin    
Calpain    
Carboxypeptidase C    
Acrosin    
Oligopeptidase B    
Thermitase    
Cathepsin B    
Cathepsin D    
Cathepsin L    
Papain    
Furin    
Granzyme B    
Tripeptide Aminopeptidase    
Cerevisin    
Subtilisin    
Thrombin (Coagulation Factor IIa)    
Trypsin    
Tryptase    
u-Plasminogen Activator    
Gingipain R    
Calpain-2    
Cathepsin T