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Availability: In stock

Dermaseptin
H-Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln-OH

H-1294

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-1294.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 100.00
CHF 93.00 (7%)
H-1294.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 180.00
CHF 167.40 (7%)
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Details

Dermaseptin was originally isolated from skin extracts of the South American arboreal frog, Phyllomedusa sauvagei. The strongly basic, nonhemolytic compound is the first vertebrate peptide that shows highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. With a potentially amphiphatic α-helix structure, dermaseptin probably acts by membrane permeabilization.
Item Number 4018008
APC Number 79-4-15
One Letter Code ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Molecular Formula C₁₅₂H₂₅₇N₄₃O₄₄S₂
Relative Molecular Mass 3455.11
CAS Registry Number [136033-70-0]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Amphibian antimicrobial and antifungal peptide