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PACAP-27 (human, mouse, ovine, porcine, rat) trifluoroacetate salt
H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂ trifluoroacetate salt

H-1172

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
H-1172.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 361.00
CHF 335.73 (7%)
H-1172.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 618.00
CHF 574.74 (7%)
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Details

PACAP-38 and its N-terminal fragment PACAP-27 are neuropeptides originally isolated from ovine hypothalamus, but also found in humans and rats. Both PACAP-27, which shows considerable homology with vasoactive intestinal polypeptide (VIP), and PACAP-38 stimulate adenylate cyclase much more potently than VIP. Specific PACAP receptors have been identified in different tissues and cell lines.Kojro et al. observed that the PAC1 agonists PACAP-27 and PACAP-38 strongly increased the activity of α-secretase, thus promoting the non-amyloidogenic processing of amyloid precursor protein.
Item Number 4031084
APC Number 34-0-40
One Letter Code HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH₂
Synonyms Pituitary Adenylate Cyclase Activating Polypeptide-27 (human, mouse, ovine, porcine, rat), PACAP-38 (1-27) amide (human, mouse, ovine, porcine, rat)
Molecular Formula C₁₄₂H₂₂₄N₄₀O₃₉S
Relative Molecular Mass 3147.65
CAS Registry Number [127317-03-7] net
Source Synthetic
Storage Conditions -20 ± 5 °C