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Availability: In stock

Cyclo(-His-Phe)

G-1740

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
G-1740.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 464.00
CHF 431.52 (7%)
G-1740.1000 1 g Ships within 3-5 business days  
CHF 1'391.00
CHF 1'293.63 (7%)
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Details

Catalyst for asymmetric cyanohydrin synthesis. The addition of hydrogen cyanide to benzaldehyde gives the highest optical yield ever obtained for the corresponding cyanohydrin.
In a study of McCleland et al., Cyclo(His-Phe) showed significant anti-tumour activity, causing reduction of cell viability in cervical cancer cells. In isolated rat hearts, the diketopiperazine caused a gradual reduction of heart rate and a decrease in coronary flow rate.
Item Number 4006752
Molecular Formula C₁₅H₁₆N₄O₂
Relative Molecular Mass 284.32
CAS Registry Number [56586-95-9]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Chiral catalyst; Anti-tumor cyclopeptide
Areas of Interest Cancer Research

Product citations

M.B.Martins and I.Carvalho, Tetrahedron, 63, 9923 (2007)
K.Tanaka et al., J. Org. Chem., 55, 181 (1990)
J.I.Oku and S.Inoue, J. Chem. Soc. Chem. Commun., (1981)