H-6542

RANTES (human)

H-Ser-Pro-Tyr-Ser-Ser-Asp-Thr-Thr-Pro-Cys-Cys-Phe-Ala-Tyr-Ile-Ala-Arg-Pro-Leu-Pro-Arg-Ala-His-Ile-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Gly-Lys-Cys-Ser-Asn-Pro-Ala-Val-Val-Phe-Val-Thr-Arg-Lys-Asn-Arg-Gln-Val-Cys-Ala-Asn-Pro-Glu-Lys-Lys-Trp-Val-Arg-Glu-Tyr-Ile-Asn-Ser-Leu-Glu-Met-Ser-OH

(Disulfide bonds between Cys¹⁰ and Cys³⁴/Cys¹¹ and Cys⁵⁰)

Trifluoroacetate salt

Synonym:
Small-Inducible Cytokine A5, CCL5, T Cell-Specific Protein P228, TCP228

C₃₅₀H₅₃₄N₉₆O₁₀₀S₅	M_r: 7847.01
Longterm storage temperature:	-20 ± 5 °C

Synthetic product. RANTES is a CC-chemokine that can signal via the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is chemotactic for T-cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).

Literature:
J.A.Levy, J. Immunol., 182, 3945 (2009)

Catalog Number	Unit	Price per Unit
H-6542.0050	50 µg	Please select your country
H-6542.1000	1 mg	Please select your country

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