H-4955
Somatostatin-28
H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH
(Disulfide bond)
| C137H207N41O39S3 | Mr: 3148.60 | [73032-94-7] |
| Longterm storage temperature: | -20 ± 5 °C | C137H207N41O39S3 |
This octacosapeptide S-28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a larger precursor, preprosomatostatin. S-28 was first isolated from porcine duodenum. In guinea-pig pancreatic acini, S-28, unlike S-14, increased amylase secretion, cellular cyclic GMP, and Ca2+ outfluxes.
Literature:
L.Pradayrol et al., FEBS Lett., 109, 55 (1980)
A.V.Schally et al., Proc. Natl. Acad. Sci. USA, 77, 4489 (1980)
N.Tahiri-Jout et al., Neuropeptides, 19, 65 (1991)
G.Bissette and B.Myers, Life Sci., 51, 1389 (1992)
L.Pradayrol et al., FEBS Lett., 109, 55 (1980)
A.V.Schally et al., Proc. Natl. Acad. Sci. USA, 77, 4489 (1980)
N.Tahiri-Jout et al., Neuropeptides, 19, 65 (1991)
G.Bissette and B.Myers, Life Sci., 51, 1389 (1992)
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