H-6542
RANTES (human)
H-Ser-Pro-Tyr-Ser-Ser-Asp-Thr-Thr-Pro-Cys-Cys-Phe-Ala-Tyr-Ile-Ala-Arg-Pro-Leu-Pro-Arg-Ala-His-Ile-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Gly-Lys-Cys-Ser-Asn-Pro-Ala-Val-Val-Phe-Val-Thr-Arg-Lys-Asn-Arg-Gln-Val-Cys-Ala-Asn-Pro-Glu-Lys-Lys-Trp-Val-Arg-Glu-Tyr-Ile-Asn-Ser-Leu-Glu-Met-Ser-OH
(Disulfide bonds between Cys¹⁰ and Cys³⁴/Cys¹¹ and Cys⁵⁰)
Trifluoroacetate salt
Synonym:
Small-Inducible Cytokine A5, CCL5, T Cell-Specific Protein P228, TCP228
| C350H534N96O100S5 | Mr: 7847.01 | |
| Longterm storage temperature: | -20 ± 5 °C | C350H534N96O100S5 |
Synthetic product. RANTES is a CC-chemokine that can signal via the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is chemotactic for T-cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).
Literature:
J.A.Levy, J. Immunol., 182, 3945 (2009)
J.A.Levy, J. Immunol., 182, 3945 (2009)
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