Neuropeptide S

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Neuropeptide S (NPS) is a modulator of arousal and possibly anxiety-related behaviour. It acts by activating its cognate receptor (NPSR) and inducing mobilization of intracellular Ca²⁺. Central administration of NPS induced wakefulness and reduced slow wave and REM sleep in rats. These peptides represent potential lead compounds for the treatment of sleep and anxiety disorders.

Family Literatur:
Y.-L.Xu et al., Neuron, 43, 487 (2004)

H-6436	Neuropeptide S (1-10) (human)
H-6162	Neuropeptide S (human)
H-6164	Neuropeptide S (rat)