Nectofibrin Peptides

Nectofibrins are 'anti-fibronectin' peptides. Their sequences have been deduced from the complementary DNA strands of the human and rat fibronectin cell binding domain. By interacting with this Arg-Gly-Asp-Ser region, both peptides efficiently inhibit the binding of fibronectin to its receptors. Antibodies produced against the nectofibrins recognize the fibronectin receptor molecule and can be used in characterization studies.

Family Literatur:
R.R.Brentani et al., Proc. Natl. Acad. Sci. USA, 85, 364 (1988)