Guanylins

Guanylin and uroguanylin are structurally related peptides which act on a transmembrane form of guanylate cyclase, termed GC-C. In mammals, they play pivotal roles in body fluid homeostasis. Less well defined additional members belonging to this family were identified in opposum and in eel.

Family Literatur:
X.Fan et al., Am. J. Physiol., 273, E957 (1997)
Z.Li et al., Regul. Peptides, 68, 45 (1997)