H-8090
Deltorphin
H-Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2
Synonym:
Deltorphin A, Dermenkephalin, Dermorphin Gene-Associated Peptide (DGAP)
| C44H62N10O10S2 | Mr: 955.17 | [119975-64-3] |
| Longterm storage temperature: | -20 ± 5 °C | C44H62N10O10S2 |
This peptide, first isolated from skin extracts of the South American frog Phyllomedusa sauvagei, corresponds to the predicted prodermorphin heptapepeptide. It acts as a highly potent and fully selective agonist for the δ-opioid receptor.
Literature:
M.Amiche et al., Mol. Pharmacol., 35, 774 (1989)
G.Kreil et al., Eur. J. Pharmacol., 162, 123 (1989)
L.H.Lazarus et al., J. Biol. Chem., 264, 3047 (1989)
A.Mor et al., FEBS Lett., 255, 269 (1989)
S.Sagan et al., J. Biol. Chem., 264, 17100 (1989)
S.Salvadori et al., J. Med. Chem., 34, 1656 (1991)
P.Melchiorri et al., Eur. J. Pharmacol., 195, 201 (1991)
H.L.Lazarus et al., J. Med. Chem., 34, 1350 (1991)
M.Amiche et al., Mol. Pharmacol., 35, 774 (1989)
G.Kreil et al., Eur. J. Pharmacol., 162, 123 (1989)
L.H.Lazarus et al., J. Biol. Chem., 264, 3047 (1989)
A.Mor et al., FEBS Lett., 255, 269 (1989)
S.Sagan et al., J. Biol. Chem., 264, 17100 (1989)
S.Salvadori et al., J. Med. Chem., 34, 1656 (1991)
P.Melchiorri et al., Eur. J. Pharmacol., 195, 201 (1991)
H.L.Lazarus et al., J. Med. Chem., 34, 1350 (1991)
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Family Description:
For other opioid peptides see Acetalins, BAM Peptides, α-Casein Exorphins, β-Casomorphins, Dynorphins, Endomorphins, Endorphins, Enkephalins, Gluten Exorphins, Kyotorphins, Metorphamide, Neoendorphins, Opioid Peptides, Opiorphins, δ Opioid Receptor Antagonists, and Valorphin.
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